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알림마당

세미나/취업안내

Seminar Announcement-Biomechanical Measurement of the Symptoms in Pakinson`s Disease

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2018.06.11

Seminar Announcement

612() 05:00PM, 하나과학관 B452

 

엄광문 교수

건국대학교 ICT융합공학부 의학공학전공

 

Aging Effect on Postural Control

It has been reported that the fall incidence in women is much higher than men and that fallers have worse postural balance performance than non-fallers. However, it is controversial whether any sex difference in postural balance performance exists. The purpose of this study was to investigate the effects of sex and age and their interactions in balance performance during quiet standing with natural stance width.

 

Biomechanical Measurement of the Symptoms in Pakinson&aposs Disease

This study aims to analyze viscoelastic properties of the wrist in patients with Parkinson’s disease (PD) in comparison with the clinical score of severity. Forty-five patients with PD and 12 healthy volunteers participated in this study. Severity of rigidity at the wrist was rated by a neurologist just before the experiment. Wrist joint torque resistive to the imposed movement was measured. Three different models, (identical in structure, only different in the number of parameters for extension and flexion phases) were used in identification of viscoelastic properties: 1) one damping constant and one spring constant throughout all phases, 2) two damping constants for each phase and one spring constant throughout all phases, and 3) two damping constants and two spring constants for each phase. Normalized work and impulse suggested in the literature were also calculated. Spring constants of different models and phases showed comparable correlation with rigidity score. In terms of the correlation of damping constant with clinical rigidity score, model 1 was better than models 2 and 3. These results suggest that the clinical rigidity score is better represented by the mean viscosity during both flexion and extension. In models with two dampers (model 2 and 3), the damping constant was greater during extension than flexion in patients, in contrast that there was no phase difference in normal subjects. This suggests that in contrast with normal subjects, phase-dependent viscosity may be an inherent feature of PD. Although work and impulse were correlated with clinical

rigidity score, they could not represent the phase-dependent rigidity inherent in PD. In conclusion, the viscosity of model 1 would be appropriate for quantification of clinical ratings of rigidity and that of model 2 for distinction of PD and also for investigation of phase-dependent characteristics in parkinsonian rigidity.